TY  - BOOK
AU  - Blackburn,G.Michael
AU  - Gait,Michael G.
TI  - Nucleic Acids in Chemistry and Biology
SN  - 9780199635337 
U1  - 574.87328 
PY  - 1997///
CY  - Oxford, England, New York
PB  - IRL Press at Oxford University Press
KW  - Nucleic acids
N1  - Originally published: New York : Oxford University Press, 1996; Includes index and Glossary

; Introduction and overview --
DNA and RNA structure --
Chemical synthesis --
Biosynthesis of nucleotides --
DNA sequence information, replication, and rearrangement --
RNA sequence information and transmission --
Covalent interactions of nucleic acids with small molecules --
Reversible interactions of nucleic acids with small molecules --
Interaction of proteins with nucleic acids --
Techniques applied to nucleic acids --
Glossary --
Index
N2  - Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Nowhere is this more apparent than in the increasing efforts to determine the DNA sequence of the human genome and the development of new diagnostics of genetic disease. Recent sophistication of nucleic acids synthesis has been key to the establishment of the biotechnology industry and our improving knowledge of nucleic acid structures and interactions is noticeably influencing the design of novel drugs.This second and completely revised edition draws on the expertise of the same international group of authors to set the basics of the nucleic acids in the context of the expanding horizons set by modern structural biology, RNA enzymology, drug discovery and biotechnology
UR  - http://www.loc.gov/catdir/enhancements/fy0636/94046592-d.html
UR  - http://www.loc.gov/catdir/enhancements/fy0639/94046592-t.html
ER  -