000 02629nam a22002294a 4500
999 _c44673
_d44673
020 _a9780120455409
020 _a0120455404 (alk. paper)
082 0 0 _a572.8
_bHAN
100 _aSatinder Ahuja
_eedt
245 0 0 _aHandbook of bioseparations /
260 _aSan Diego, CA :
_bAcademic Press,
_c2000.
300 _axiv, 722 p. :
_bill. ;
490 1 _aSeparation science and technology ;
500 _aIncludes index
505 _aBioseparations : an overview / S. Ahuja -- Analysis of protein impurities in pharmaceuticals derived from recombinant DNA / Donald O. O'Keefe -- Physicochemical factors in polypeptide and protein purification and analysis by high-performance liquid chromatographic techniques : current status and challenges for the future / Milton T.W. Hearn -- Capillary electrophoresis of compounds of biological interest / S. Ahuja -- Isoelectric focusing / David E. Garfin -- Mass spectrometry of biomolecules / Dan Gibson and Catherine E. Costello -- Liquid-liquid partitioning methods for bioseparations / Tingyue Gu -- Separation of nucleic acids and proteins / Rohit Harve and Rakesh Bajpai -- Bioseparations by displacement chromatography / Steven M. Cramer -- Physicochemical basis of expanded-bed adsorption for protein purification / B. Mattiasson and M.P. Nandakumar -- Expanded-bed adsorption process for protein capture / Joseph Shiloach and Robert M. Kennedy -- Adsorptive membranes for bioseparations / Ranjit R. Deshmukh and Timothy N. Warner -- Simulated moving-bed chromatography for biomolecules / R.M. Nicoud -- Large-scale chromatographic purification of ougonucleotides / Ranjit R. Deshmukh, William E. Leitch II, Yogesh S. Sanghvi and Douglas L. Cole -- Separation of antibodies by liquid chromatography / Egisto Boschetti and Alois Jungbauer -- Processing plants and equipment / P. Bowles -- Engineering process control of bioseparation processes / Randel M. Price and Ajit Sadana -- Economics of bioseparation processes / Anand Ramakrishnan and Ajit Sadana -- Future developments / S. Ahuja.
520 _aCovers the separation of proteins, nucleic acids, and oligonucleotides from biological matrices from analytical to process scales. This work includes the separation of monoclonal antibodies, and highlights the application of DNA chip arrays. It also details selection of plant and process equipment, and addresses the economic considerations
650 0 _aBiomolecules
700 1 _aAhuja, Satinder,
856 4 2 _uhttp://www.loc.gov/catdir/description/els031/00102786.html
856 4 1 _uhttp://www.loc.gov/catdir/toc/els031/00102786.html
942 _cREF